The option to use statically-linked QEMU is being worked on. That seems to have stalled a bit due to merge conflicts but #300070 rebased the changes and is currently active.
I think the wrapper handles the binfmt_misc P flag (see here for more details, ctrl-f for preserve-argv), and prevents LD_* environment variables intended to be passed to the emulated binary from affecting QEMU itself. Newer versions of QEMU handle the P flag natively (see this commit) and LD_* is irrelevant to statically-linked executables anyway, so the PR I linked to above also disables the wrapper when you are using qemu-user-static.