I’ve been using ComfyUI for weeks now with this configuration and following the manual installation, using uv pip install.
environment.systemPackages = [
pkgs.uv
]
programs.nix-ld = {
enable = true;
libraries = [ config.boot.kernelPackages.nvidia_x11 ];
}
Most custom nodes work fine, there’s just one glaring issue: import cv2. When I start ComfyUI with uv run python main.py I get this error:
File "/home/user/Assets/ComfyUI/custom_nodes/comfyui-easy-use/py/nodes/image.py", line 1799, in <module>
import cv2
ImportError: libxcb.so.1: cannot open shared object file: No such file or directory
Apparently many other users have issues with opencv as well. I found one workaround: running comfyui inside nix-shell -p python313Packages.opencv4Full, it doesn’t work when I addpython313Packages.opencv4Full to programs.nix-ld.libraries.