I can't update NixOS anymore because of webkitgtk manual compilation

Could be that you’re overriding something, importing nixpkgs from a fetchurl somewhere, or fail to use nix flake update correctly. Or it’s a build failure in hydra that means audacity isn’t currently actually cached. A quick glance at hydra looks like audacity is passing, but I’m awful at browsing hydra.

I’d suggest you create a new post and share your configuration.