Need help on how to handle macos and python2 for tensorflow-bin update

I have some question converning the tensorflow-bin package. I was able to make it run using the version in nixpkgs with jupyter (both version 1 and 2 on different kernel, see here for the config: )

I want to update nixpkgs, hoping it will solve conflit (and updating the cudatool version too). However there are two change in the latest version 1 and 2:
First, python2.7 is not supported. It is fine if I remove support for this python version, or should I use the last version where this python is supported ?
There are multiple package for mac: macosx_10_9_x86_64, macosx_10_14_x86_64 and macosx_10_6_intel . How does I handle those various version ?

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