I wrote a blog article with the same title as this post.
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Re: unlinked object files — I have thought about that for cutting LibreOffice into parts (and claiming it is exceptional, so a local refactoring, not Nixpkgs wide, makes sense for the largest packages), but another consideration is that the intermediate files, a lot of them, would get pushed to the binary cache. (Although for a global refactoring this will probably still be a reduction overall, for local experimentation it is not as clear)